The Origin of 2-HOBA

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Revealing the Benefits of Buckwheat

Buckwheat is an ancient plant that was first cultivated in Asia and has been used in Traditional Southeast Asian medicine for thousands of years. Consumption of buckwheat is associated with a number of health benefits including greater antioxidant activity, protection against inflammation, and maintained cardiovascular and metabolic health.

Researchers interested in how buckwheat exerts these health benefits have characterized the nutrition profile of the buckwheat plants and its seeds. We now know that buckwheat contains a large number of phytonutrients. These phytonutrients protect plants from damage caused by their environments, and, as it turns out, may help support human health in a similar way.

One unique phytonutrient identified in buckwheat was 2-HOBA, or 2-hydroxybenzylamine, which is very rarely found in other foods. When scientists studied the specific effects of 2-HOBA, they found that 2-HOBA can block the formation of harmful molecules in the body.  While it’s unclear if 2-HOBA is responsible for the health benefits of buckwheat, we do know that 2-HOBA, on its own, has a number of beneficial effects.

Learn more about the benefits of 2-HOBA here .


Koyama et al. Identification of hydroxybenzylamines in buckwheat seeds (Fagopyrum esculentum Moench). Agricultural and Biological Chemistry, 35(12), 1870-1879, 1971.