Researched and Patented Dietary Ingredient

Hobamine a radical approach to cellular health

What is Hobamine?

A foundational approach to health and wellness.

Advances in science have allowed us to live longer than previous generations. Sadly, that doesn’t mean that our quality of life is always maintained as we age.


Lifespan healthspan

Our cells are the building blocks of life.  All health starts with our cells.  The healthier our cells, the healthier our bodies.  Simply put, cellular health is the most foundational approach to overall health.


That’s why we’ve created the innovative ingredient Hobamine.  Hobamine, or 2-hydroxybenzylamine (2-HOBA), is a naturally occurring compound that is at the forefront of new developments to support cellular health, particularly as we age.


How does it work?

We’ve all heard of oxidative stress. Before we get into more details it is important to know that occasional higher levels of oxidative stress are easily managed by our bodies. 


However, there are factors in our lives that can cause excess oxidative stress. Poor nutrition, drinking, environmental factors, and aging are all components that impact oxidative stress. When we have excess oxidative stress for extended periods of time, it can impact our overall health.


Hobamine (2-HOBA) works by rapidly capturing specific reactive compounds formed by oxidative stress.   This capture prevents those compounds from binding to and damaging other cellular components like proteins, lipids, or DNA and impeding normal function of the cell.  

Hobamine has been shown to promote normal cell function in brain cells, blood vessels, and heart, lung, and immune cells from the effects of oxidative stress, which helps to support healthy function.

Hobamine - the defender of every cell and every body.

Why do we need to supplement with Hobamine? 

While we can do our best to minimize oxidative stress by leading a healthy, active lifestyle, there will always be circumstances out of our control (from environmental factors like pollution or radiation to simply growing older).  We cannot reduce all stress from our lives. 

Without Hobamine (2-HOBA) supplementation, compounds formed from oxidative stress can run rampant in our cells, binding to and irreparably changing cellular components like lipids, proteins, and DNA. These changes result in the impaired function of these cellular components.

Hobamine captures these compounds formed from oxidative stress without interfering with normal, healthy free radical and ROS signaling.

Free radicals often get a bad rap, but it turns out that we need free radicals to be healthy. Free radicals are used as a signaling system by our cells to send messages around the cell and between cells as well as utilized by our immune system.

Hobamine allows free radicals to perform their roles and works downstream to trap particularly reactive compounds formed during oxidative stress.  Once these reactive compounds are sequestered, they cannot bind to other cellular components. Thus, many of the negative effects of ROS can be prevented without interfering with the important biological functions of ROS.  

Because every body is made up of cells and experiences oxidative stress, supplementing with Hobamine is relevant to everyone.  It is the NEW daily essential!  And supporting cellular health with Hobamine is a key part of taking a foundational approach to health and wellness.

Understanding Cell Health

You are made up of trillions of cells.  Those cells are the building blocks of your body.

The cell is the basic building block of all living things. Cells form tissues, tissues form organs, and organs form the systems that make up our bodies.  In order for our organs and systems to function properly, our cells first need to function optimally.  Everything that happens in our bodies starts on a cellular level.

There are more than 200 different types of specialized cells in the human body that make up our tissues and organs.  Our tissues and organs all work together to control the body’s functions like metabolism, movement, repair, etc.  That’s why taking care of yourself at a cellular level is important.  

The healthier our cells, the healthier our bodies.

Over time and as we age, there is a significant change in the way that our cells function.  These changes manifest in our bodies by affecting the way we look, feel, and function.  You may notice that your metabolism has slowed down, your immune system is unbalanced, or that you’re moving slower, losing your fitness, or aren’t able to do the things that you used to do.  These are all signs of suboptimal cellular health.

Want to dive deeper into cellular health?
Check out our Cellular Health FAQ.

NEW Study Shows 2-HOBA Supplementation has a Promising Impact on Immune Health

A NIH-funded study on the impact of 2-HOBA evaluated TSI’s branded Hobamine ingredient on inflammatory biomarkers. 

Scientists found that supplementing with 2-HOBA affected the levels of 15 inflammatory biomarkers in healthy individuals, supporting the potential of 2-HOBA to benefit immune cells and promote a healthy balance of the immune system.

Results indicated that 2-HOBA significantly improved levels of as many as 15 protein biomarkers that play important roles in immune function regulation, including TNFβ, IL12β and CCL19, which contribute to immune system homeostasis or readiness. Furthermore, the study found that 2-HOBA decreased levels of TWEAK, a protein that promotes inflammation and cell death.

To learn more about the study please visit our science section.

Oxidative Stress, Inflammation and its role in Cellular Health

Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue stress.  Oxidative stress occurs naturally and everyone experiences it. Excess oxidative stress can be caused by factors like poor nutrition, excess alcohol, smoking, obesity, stress, lack of sleep, UV sunlight, environmental factors, and even too much exercise.  Sometimes combinations of these factors result in too much oxidative stress, and these effects can be exacerbated by age.  


When oxidative stress persists, it can activate signaling pathways involved with inflammation.  If inflammation isn’t resolved, it can lead to a progression of several harmful outcomes and have a cascading effect on our well-being.  

Life is a game
of balance and

Balance means both sides of an equation are properly weighted. Balance is important in all aspects of life: work vs leisure, activity vs rest, social vs individual time. When the two sides do not align, things can get out of whack.  Just like with other aspects of our lives, our cells can become imbalanced, too, and one effect of an imbalanced cell is a buildup of highly reactive molecules called free radicals.


Free radicals are atoms or molecules that contain an unpaired (free) electron.  The free electron can make the radical unstable and reactive. Some unstable free radicals are reactive oxygen species (ROS) and having too many of these can lead to oxidative stress.  If it persists over a long period of time, this oxidative stress can negatively impact the health of our cells and bodies.


The human body is a complex machine

Not all free radicals are inherently bad, in fact they are a normal part of biology.  While carrying out the normal (balanced) cellular processes that keep us alive, our cells organically form all kinds of free radicals.  These free radicals aren’t accidental; they actually play important roles in cell communication and cell health.  Free radicals’ reactivity allows them to eliminate harmful compounds.

In a healthy, balanced cell, free radicals are balanced by antioxidants that keep radicals’ activity in check. But when free radicals overwhelm the body’s ability to regulate them, chaos ensues, and compounds called isolevuglandins are agents of this chaos. 


IsoLGs are highly reactive compounds that result from free radical oxidation of cellular lipids.  IsoLGs have an affinity for grabbing onto DNA or protein in your cells and affect their normal function. This can wreak havoc on the body because DNA is the body’s instruction manual and everything in the body is made of or contains proteins.  

IsoLGs can negatively impact heart health, lung health, brain health and a lot more…

What can we do to protect ourselves?  Is there a molecule that can grab IsoLGs? 


Yes, Hobamine.

Antioxidants vs. Hobamine

Antioxidants are molecules that are known to prevent reactions caused by ROS or free radicals.  Our bodies naturally make antioxidants to balance free radical reactivity. Many people also take antioxidants in an attempt to reduce oxidative stress, but this approach may actually block normal physiological functions and pathways.  

Interfering this far upstream has the potential to disrupt desired cellular processes driven by mild oxidative stress.  Antioxidants can impede normal functions that are vital for cell signaling and immune defense.

Hobamine helps the body maintain its normal, important physiological processes, by acting before the oxidative stress can impact your cells.

Built for Everyone
and Every body

The great news about the patented ingredient Hobamine is that it is made for EVERYONE.

Now that we are living longer, it’s even more important to maintain our health as we age. The structure, function, and process within our cells change over time as we age, and much of this is related to the build-up of reactive oxygen species which cause oxidative stress. Poor nutrition, lack of exercise, and other environmental factors all increase oxidative stress that can lead to oxidative damage and even premature aging. This presents a challenge for many, particularly those of us who have a fast-paced lifestyle.

Hobamine is the right solution for everyone experiencing the signs of premature aging due to oxidative stress.

Hobamine is the right solution for everyone looking to proactively support their cells against free radicals. It is a new daily essential. A radical approach to cellular health.

Want to try it for yourself?
Follow the link for products that exclusively license Hobamine.